Publications

Fullsize Paper

• Depboylu C, Schorlemmer K, Klietz M, Oertel WH, Weihe E, Höglinger GU, Schäfer
  MK (2011) Upregulation of microglial C1q expression has no effects on nigrostriatal
  dopaminergic injury in the MPTP mouse model of Parkinson disease. J.
  Neuroimmunol. 236:39-46.
• Matusch A, Fenn LS, Depboylu C, Klietz M, Strohmer S, McLean JA, Becker JS
  (2012) Combined elemental and biomolecular mass spectrometry imaging for probing
  the inventory of tissue at a micrometer scale. Anal. Chem. 84: 3170-3178.
• Sussulini A, Matusch A, Klietz M, Bauer A, Depboylu C, Becker JS (2012)
  Quantitative imaging of Cu, Fe, Mn and Zn in the L-DOPA-treated unilateral 6-
  hydroxydopamine Parkinson’s disease mouse model by LA-ICP-MS. Biomedical
  Spectroscopy and Imaging 1: 125-136.
• Schäfer MK, Hartwig NR, Kalmbach N, Klietz M, Anlauf M, Eiden LE, Weihe E
  (2013) Species-specific vesicular monoamine transporter 2 (VMAT2) expression
  inmammalian pancreatic beta cells: implications for optimising radioligand-based
  human beta cell mass (BCM) imaging in animal models. Diabetologia 56:1047-1056.
• Depboylu C, Klietz M, Maurer L, Oertel WH, Kobayashi K, Weihe E, Höglinger GU,
  Schäfer MK (2014) Transcriptional and structural plasticity of tyrosine hydroxylase
  expressing neurons in both striatum and nucleus accumbens following dopaminergic
  denervation. J. Chem. Neuroanatomy 61-62:169-175.
• Keber U, Klietz M, Carlsson T, Oertel WH, Weihe E, Schäfer MK, Höglinger GU,
  Depboylu C (2015) Striatal tyrosine hydroxylase-positive neurons are associated with
  L-DOPA induced dyskinesia in hemiparkinsonian mice. Neuroscience 298:302-17.
• Klietz M, Keber U, Carlsson T, Chiu W-H, Höglinger GU, Weihe E, Schäfer M K-H,
  Depboylu C (2016) L-DOPA-induced dyskinesia is associated with a deficient
  numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons.
  Neuroscience 331:120-133.
• Klietz M, Tulke A, Müschen LH, Paracka L, Schrader C, Dressler DW, Wegner F.
  (2018) Impaired Quality of Life and Need for Palliative Care in a German Cohort of
  Advanced Parkinson’s Disease Patients. Front Neurol. 2018 Mar 6;9:120. doi:
  10.3389/fneur.2018.00120.
• Stanslowsky N, Tharmarasa S, Staege S, Kalmbach N, Klietz M, Schwarz SC, Leffler
  A, Wegner F. Calcium, Sodium, and Transient Receptor Potential Channel Expression
  in Human Fetal Midbrain-Derived Neural Progenitor Cells. Stem Cells Dev. 2018 Jul
  15;27(14):976-984.
• Klietz M, Rippena L, Lange F, Tulke A, Paracka L, Dressler D, Wegner F (2019).
  Validating the Parkinson’s disease caregiver burden questionnaire (PDCB) in German
  caregiver of advanced Parkinson’s disease patients. International Psychogeriatrics.
  2019 Mar 25:1-10. doi: 10.1017/S1041610219000206.
• Klietz M, Greten S, Wegner F, Höglinger GU (2019). Safety and Tolerability of
  Pharmacotherapies for Parkinson’s Disease in Geriatric Patients. Drugs and Aging.
  2019 Apr 2. doi: 10.1007/s40266-019-00654-z.
• Paracka L, Kollewe K, Klietz M, Petri S, Dressler D. IncobotulinumtoxinA for
  hypersalivation in patients with amyotrophic lateral sclerosis: an open-label singlecentre study. J Neural Transm (Vienna). 2019 Oct;126(10):1341–5.
• Klietz M, Bronzlik P, Nösel P, Wegner F, Dressler DW, Dadak M, Maudsley AA,
  Sheriff S, Lanfermann H, Ding X. Altered Neurometabolic Profile in Early Parkinson’s
  Disease: A Study With Short Echo-Time Whole Brain MR Spectroscopic Imaging.
  Front Neurol. 2019 Jul 17;10:406–11.
• Klietz M, Öcalan Ö, Schneider N, Dressler D, Stiel S, Wegner F. Advance Directives
  of German People with Parkinson’s Disease Are Unspecific in regard to Typical
  Complications. Parkinson’s Disease. Hindawi; 2019 Aug 4;2019:1–8.
• Drexel SC, Klietz M, Kollewe K, Paracka L, Kutschenko A, Kopp B, Lange F, Wegner
  F, Dressler D. Caregiver burden and health-related quality of life in idiopathic dystonia
  patients under botulinum toxin treatment: a cross-sectional study. J Neural Transm.
  Springer Vienna; 2020 Jan;127(1):61–70.
• Piot I, Schweyer K, Respondek G, Stamelou M, ProPSP Study Group, Sckopke P,
  Schenk T, Goetz CG, Stebbins GT, Höglinger GU. The Progressive Supranuclear Palsy
  Clinical Deficits Scale. Mov Disord. 2020 Apr;35(4):650–61.
• Klietz M, Drexel SC, Schnur T, Lange F, Groh A, Paracka L, Greten S, Dressler D,
  Höglinger GU, Wegner F. Mindfulness and Psychological Flexibility are Inversely
  Associated with Caregiver Burden in Parkinson’s Disease. Brain Sciences.
  Multidisciplinary Digital Publishing Institute; 2020 Feb;10(2):111–10.
• Klietz M, Berndt JM, Wegner F, Schneider N, Höglinger GU, Eggers C, Stiel S.
  Consensus-Based Recommendations for Advance Directives of People with
  Parkinson’s Disease in Regard to Typical Complications by German Movement
  Disorder Specialists. JCM. Multidisciplinary Digital Publishing Institute; 2020
  Feb;9(2):449–14.
• Klietz M, Schnur T, Drexel S, Lange F, Tulke A, Rippena L, Paracka L, Dressler D,
  Höglinger GU, Wegner F. Association of Motor and Cognitive Symptoms with Health-
  Related Quality of Life and Caregiver Burden in a German Cohort of Advanced
  Parkinson’s Disease Patients. Parkinson’s Disease. Hindawi; 2020 Feb 24;2020:1–8.
• Kutschenko A, Klietz M, Paracka L, Kollewe K, Schulte-Sutum A, Janssen T, Schrader
  C, Wegner F, Dressler D. Dysphagia in cervical dystonia patients receiving optimised
  botulinum toxin therapy: a single-center retrospective cohort study. J Neural Transm
  (Vienna). 2020;127(8):1161-1165.
• Klietz M, Schnur T, Drexel SC, Lange F, Paracka L, Huber MK, Dressler D, Höglinger
  GU, Wegner F. Alexithymia Is Associated with Reduced Quality of Life and Increased
  Caregiver Burden in Parkinson’s Disease. Brain Sci. 2020;10(6):401. Published 2020
  Jun 24.
• Paracka L, Wegner F, Escher C, Klietz M, de Zwaan M, Abdalat M, Saryyeva A,
  Krauss JK. Body Concept and Quality of Life in Patients with Idiopathic
  Dystonia. Brain Sci. 2020;10(8):E488. Published 2020 Jul 28. Doi:
  10.3390/brainsci10080488
• Fu T, Klietz M, Nösel P, Wegner F, Schrader C, Höglinger GU, Dadak M, Mahmoudi
  N, Lanfermann H, Ding X. Brain Morphological Alterations Are Detected in Early‐
  Stage Parkinson’s Disease with MRI Morphometry. Journal of Neuroimaging. 2020
  Aug 17;2020:231–7.
• Greten S, Müller-Funogea JI, Wegner F, Höglinger GU, Simon N, Junius-Walker U,
  Gerbel S, Krause O, Klietz M. Drug safety profiles in geriatric patients with
  Parkinson’s disease using the FORTA (Fit fOR The Aged) classification: results from
  a mono-centric retrospective analysis. J Neural Transm (Vienna). 2021 Jan;128(1):49-
  60.
• Grötsch MT, Respondek G, Colosimo C, Compta Y, Corvol JC, Ferreira J, Huber
  MK, Klietz M, Krey LFM, Levin J, Jecmenica-Lukic M, Macías-García D, Meissner
  WG, Mir P, Morris H, Nilsson C, Rowe JB, Seppi K, Stamelou M, van Swieten JC,
  Wenning G, Del Ser T, Golbe LI, Höglinger GU; DescribePSP Study Group, the
  ProPSP Study Group, and the Movement Disorder Society-Endorsed PSP Study Group.
  A Modified Progressive Supranuclear Palsy Rating Scale. Mov Disord. 2021 Jan 29.
• Klietz M, von Eichel H, Schnur T, Staege S, Höglinger GU, Wegner F, Stiel S One
  Year Trajectory of Caregiver Burden in Parkinson’s Disease and Analysis of GenderSpecific Aspects. Brain Sci. 2021 Feb 26;11(3):295.
• Klietz M, Eichel HV, Staege S, Kutschenko A, Respondek G, Huber MK, Greten S,
  Höglinger GU, Wegner F. Validation of the Parkinson’s Disease Caregiver Burden
  Questionnaire in Progressive Supranuclear Palsy. Parkinsons Dis. 2021 May
  10;2021:9990679. eCollection 2021.
• Staege S, Kutschenko A, Baumann H, Glaß H, Henkel L, Gschwendtberger T,
  Kalmbach N, Klietz M, Hermann A, Lohmann K, Seibler P, Wegner F. Reduced
  Expression of GABA A Receptor Alpha2 Subunit Is Associated With Disinhibition of
  DYT-THAP1 Dystonia Patient-Derived Striatal Medium Spiny Neurons. Front Cell
  Dev Biol. 2021 May 21;9:650586. eCollection 2021.
• Heine J, von Eichel H, Staege S, Höglinger GU, Wegner F, Klietz M. Relationship
  satisfaction in People with Parkinson’s disease and their caregivers: a cross-sectional
  observational study. Brain Sci. 2021 Jun 21;11(6):822.
• Schulz JB, Berlit P, Diener HC, Gerloff C, Greinacher A, Klein C, Petzold GC,
  Piccininni M, Poli S, Röhrig R, Steinmetz H, Thiele T, Kurth T; German Society of
  Neurology SARS-CoV-2 Vaccination Study Group. COVID-19 Vaccine-Associated
  Cerebral Venous Thrombosis in Germany. Ann Neurol. 2021 Oct;90(4):627-639. Epub
  2021 Aug 23.
• Klietz M, Elaman MH, Mahmoudi N, Nösel P, Ahlswede M, Wegner F, Höglinger
  GU, Lanfermann H and Ding X-Q (2021) Cerebral Microstructural Alterations in
  Patients With Early Parkinson’s Disease Detected With Quantitative Magnetic
  Resonance Measurements. Front. Aging Neurosci. 13:763331.
• Jensen I, Lescher E, Stiel S; Wegner F; Höglinger G; Klietz M. Analysis of Transition
  of Patients with Parkinson’s Disease into Institutional Care: A Retrospective Pilot
  Study. Brain Sci. 2021, 11, 1470.
• Krey L, Lange P, Tran AT, Greten S, Höglinger GU, Wegner F, Krause O, Klietz M.
  Patient Safety in a Box: Implementation and Evaluation of the Emergency Box in
  Geriatric and Parkinson Patients. J Clin Med. 2021 Nov 29;10(23):5618.
• Eichel HV, Heine J, Wegner F, Rogozinski S, Stiel S, Groh A, Krey L, Höglinger
  GU, Klietz M. Neuropsychiatric Symptoms in Parkinson’s Disease Patients Are
  Associated with Reduced Health-Related Quality of Life and Increased Caregiver
  Burden. Brain Sci. 2022 Jan 11;12(1):89.
• Sophia Rogozinski, Martin Klietz, Gesine Respondek, Wolfgang H. Oertel, Michel J.
  Grothe, Joana B. Pereira, Günter U Höglinger. Reduction in volume of nucleus basalis
  of Meynert is specific to Parkinson’s disease and Progressive supranuclear palsy but
  not to Multiple system atrophy. Front. Aging Neurosci., (2022).

Review Paper

• Klietz M, Greten S, Wegner F, Höglinger GU. Safety and Tolerability of
  Pharmacotherapies for Parkinson’s Disease in Geriatric Patients. Drugs and Aging.
  2019 Apr 2.

Teaching Paper

• Klietz M, Höglinger GU. 56/m mit therapierefraktärem akinetisch-rigiden Syndrom. DGNeurologie 2020, 3(1), 65-67.
• Klietz M. Wirkfluktuationen unter initialer Therapie mit Levodopa: Wie geht die Reise weiter? Neurodiem 2022.

Abstracts

• Klietz M, Depboylu C, Höglinger GU, Kobayashi K, Weihe E, M. Schäfer MK. (2011).
  Phenotypic Traits of Striatal Neurons Expressing Tyrosine Hydroxylase and Effects of
  Nigrostriatal Dopamine Pathway Injury. 7th IBRO Meeting Florence, Italy.
• Klietz M, Depboylu C, Höglinger, Kobayashi K, Weihe E, M. Schäfer MK. (2011).
  Tyrosine hydroxylase-positive interneurons in mouse striatum express both VMAT2
  and VIAAT and exhibit plasticity for dynorphin. SFN Neuroscience Abstract,
  Washington, D.C., US.
• Klietz M, Keber U, Carlsson T, Chiu W, Schäfer MK, Depboylu C (2012). Striatal
  Tyrosine Hydroxylase Positive Neurons are Regulated in a Mouse Model of L-DOPA
  Induced Dyskinesia 8th FENS Forum of Neuroscience, July 14th-18th, Barcelona, Spain.
• Klietz M, Depboylu C, Chiu W, Kobayashi K, Weihe E, M. Schäfer MK. (2013).
  Expression analysis of dopaminergic marker genes in tyrosine hydroxylase positive
  neurons in the striatum of TH-eGFP mice by laser microdissection. Abs. T11-12C,
  Göttingen Meeting of the German Neuroscience Society 2013, Göttingen, Germany.
• Keber U, Klietz M, Oertel WH, Höglinger GU, Carlsson T, Depboylu C (2014). Striatal
  tyrosine hydroxylase-positive neurons trigger L-DOPA-induced dyskinesia in mice.
  Neurowoche München, Germany.
• M. Klietz, U. Keber, T. Carlsson, G. U. Höglinger, M.K-H Schäfer, E. Weihe and C.
  Depboylu (2016). L-DOPA-induced dyskinesia is associated with a deficient numerical
  downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons DGN
  Congress Mannheim, Germany.
• Klietz M, Tulke A, Müschen LH, Schrader C, Dressler DW, Wegner F (2017).
  Versorgungssituation und Lebensqualität schwer betroffener Parkinsonpatienten unter
  palliativmedizinischen Aspekten. Deutscher Parkinsonkongress Baden-Baden,
  Germany.
• Klietz, M.; Tulke, A.; Schrader C.; Diekstall, L.; Müschen, L.; Dressler, D.; Wegner,
  F. (2017) Quality of life and influencing factors in a local population of advanced
  geriatric Parkinson´s Disease patients. Movement Disorder Society 2017 Vancouver.
• M. Klietz, A. Tulke, L. Diekstall, L. Müschen, C. Schrader, D. Dressler, F. Wegner
  (2017). Palliative care and quality of life in a German cohort of geriatric patients with
  advanced Parkinson´s disease. DGN Congress Leipzig, Germany.
• Diekstall, L.; Klietz, M.; Tulke, A.; Lange, F; Schrader C.; Dressler, D.; Wegner, F.
  (2017). Caregiver burden of relatives from advanced Parkinson´s disease patients.
  DGN Congress Leipzig, Germany.
• M. Klietz, P. Bronzlik, B. Schmitz, F. Wegner, D. Dressler, M. Dadak, XQ Ding
  (2018). Whole brain spectroscopy in early Parkinson’s disease: an exploratory MRI
  study. DGN Congress Berlin, Germany.
• Drexel S, Klietz M, Kollewe K, Paracka L, Kutschenko A, Schulte-Sutum A, Kopp
  B, Lange F, Wegner F, Dressler D (2019) Dystonia treated with Botulinum Toxin:
  Quality of Life and Caregiver Burden. Toxins, Copenhagen, Denmark.
• Klietz M., Schnur T., Drexel S.C., Lange F., Paracka L., Dressler D., Höglinger G.U.,
  Wegner F. (2020). Alexithymia is associated with worse quality of life and caregiver
  burden in people with Parkinson’s disease. Movement Disorders (virtual Meeting).
• Drexel S.C., Wegner F., Schnur T., Lange F., Paracka L., Dressler D., Höglinger G.U.,
  Klietz M. (2020). Achtsamkeit und psychologische Flexibilität sind invers mit der
  subjektiven Belastung pflegender Angehöriger von Patienten mit Morbus Parkinson
  assoziiert. DGN Kongress, Berlin.
• Schnur T., Wegner F., Drexel S.C., Lange F., Tulke A., Rippena L., Paracka L.,
  Dressler D., Höglinger G.U., Klietz M. (2020). Assoziation motorischer und kognitiver
  Symptome mit der gesundheitsbezogenen Lebensqualität von Parkinson-Patienten und
  der Belastung ihrer betreuenden Angehörigen in einer Kohorte fortgeschrittener
  Parkinson-Patienten. DGN Kongress, Berlin.Symposium
• PD Dr. Klietz, Prof. Dr. Lorenzl „Caregiver Burden bei chronischen
  Bewegungsstörungen“ Deutscher Parkinsonkongress Hannover/online 2022.